Abstract: Objective To investigate the effect of gastric bed interstitial tissue chemotherapy during the operation on progressive gastric cancer.Methods 164 patients with progression gastric cancer were divided into two groups randomly,84 in therapy group and 80 in control group.The patients' survival rate,no tumor survival rate and relapsing rate of the two groups were observed.Results Between the two groups,the survival rate was not dramatic different in the first year(P>0.05).The survival rate and no tumor survival rate in the second and third years were significantly superior in therapy group than that in control group(P<0.05).The relapse rate in therapy group was also superior than that in control group(P<0.05).Conclusions Chemotherapy on gastric bed interstitial tissue during the operation on progressive gastric cancer can dramatically raise patients' survival rate and survival quality.It can also decrease the relapse rate after operation.

Key words: Progressive gastric cancer, Operation, Gastric bed, Interstitial tissue chemotherapy