Abstract:

 Objective To investigate the impact of the duration and frequency of Pringle′s maneuver on postoperative serum amylase levels in patients undergoing hepatectomy. Methods Retrospective analysis of 87 patients who underwent hepatic resection using the Pringle′s maneuver at our hospital from January 2013 to June 2015 were assigned to normal or hyperamylasemia groups based on postoperative serum amylase levels. Then the two groups were compared in terms of Pringle’s frequency，Pringle duration，and length and costs of hospitalization. Results Postoperative serum amylase levels were slightly increased in 12 patients，elevated in 29，and hyperamylasemic in 17. Pringle′s frequency was significantly longer in the hyperamylasemia group than in the normal group（5.3±3.0 vs 3.8±2.4，P=0.043），while Pringle′s duration was similar between the two groups （73.1±47.1 vs 58.0±42.7 min，P=0.233）. Length of hospitalization was similar between the two groups（P=0.498），while total cost of hospitalization differed significantly between the two groups（P=0.001）. Conclusion Pringle′s maneuver may increase risk of postoperative hyperamylasemia，which increases the total cost of hospitalization.

Key words: Hepatectomy, Pringle′s maneuver, Serum amylase