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Chinese Journal of Oncology Prevention and Treatment

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Efficacy of transcatheter hepatic arterial chemoembolization and intravenous chemotherapy on patients with liver metastases from colorectal cancer

SHUI Hui-feng,GE Lian-ying .   

  1. (Graduate School of Guangxi Medical University,Tumor Hospital of Guangxi Medical University,Nanning 530021,China
  • Received:2010-03-25 Revised:2010-03-25 Online:2010-03-25 Published:2010-03-25

Abstract: Objective To analyze the efficacy of transcatheter hepatic arterial chemoembolization(TACE) and intravenous chemotherapy on liver metastases from colorectal cancer,by comparing short-and long-term therapeutic effect on the patients.Methods 62 patients with liver metastases from colorectal cancer were divided into two groups.17 patients who were treated by TACE were defined as TACE group,and the other group included 45 patients who received intravenous chemotherapy.The follow-up Results on therapeutic effect and survival rate from the two groups were compared.Results The short-term efficacy rate in TACE group was 64.7%,while it was 33.3% in intravenous chemotherapy group.The 1-,2-,3-and 5-year survival rates in the group of TACE were 82.4%,32.4%,12.9% and 0,versus 59.6%,19.3%,7.4% and 0 in the group of intravenous chemotherapy.Conclusions TACE and intravenous chemotherapy are effective,safe and alternative treatment for liver metastases from colorectal cancer in which the tumor can not be removed.Short-term therapeutic effect of TACE is better than that of intravenous chemotherapy,but the survival rates of the two treatments are similar.

Key words: Colorectal carcinoma, Hepatic metastasis, Transcatheter hepatic arterial chemoembolization, Chemotherapy