Abstract:

Objective To explore risk factors for hospital infections following craniotomy to treat intracranial tumors and to assess potential prevention measures. Methods Medical records were retrospectively reviewed for 288 patients treated between January 2014 and June 2016 at the Affilated Tumor Hospital of Guangxi Medical University. Potential risk factors for hospital infection were identified. Results Nosocomial infection occurred in 41 of 288 patients（14.24%），comprising 27 pulmonary infections，7 intracranial infections，3 urinary tract infections，2 blood infections，and 2 incision infections. Univariate anlysis identified the following risk factors for nosocomial infection：surgical site，operation time，drainage tube indwelling time，and surgical transfusion. Multivariate logistic regression identified the following independent risk factors：surgical site，drainage tube indwelling time longer than two days，and blood transfusion. Conclusion The rate of nosocomial infection among patients undergoing intracranial tumor craniotomy at our hospital was relatively high（14.24%），and lung was the main infection site. Risk of nosocomial infection was particularly high among patients who underwent infratentorial removal of intracranial tumors or intra-operative blood transfusion，or who had a postoperative drainage time longer than 2 days. These results suggest that should take reasonable measures to reduce incidence of nosocomial infection.

Key words: Intracranial neoplasms, Craniotomy, Nosocomial infection, Related factors