Abstract: Objective To compare the clinical efficacy of local microwave ablation combined with percutaneous kyphoplasty and conventional percutaneous kyphoplasty in the treatment of advanced acetabular metastases. Methods A total of 32 patients with advanced acetabular metastases received treatment in Guangxi Medical University Cancer Hospital from December 2015 to January 2020 were selected, and divided into local microwave ablation combined with percutaneous kyphoplasty group (observation group) and percutaneous kyphoplasty group (control group). The differences between two treatment methods were compared based on operation time, intraoperative bleeding loss, visual analogue scale (VAS) of pain and postoperative complications. Results No significant differences were found in operative time, intraoperative blood loss, postoperative bed rest, preoperative VAS scores and changes between the two groups (P>0.05). Compared with the control group, the postoperative VAS score in the observation group was reduced ［(3.43±0.50) scores vs (4.87±0.44) scores, P=0.042］. The overall incidence of postoperative complications (18.8% vs 75.0%, P<0.001) and the postoperative recurrence rate (6.3% vs 43.7%, P=0.04) were lower than those in the control group. Conclusions Local microwave ablation combined with percutaneous kyphoplasty in the treatment of advanced acetabular metastatic tumors can reduce postoperative pain and recurrence rate. It is a safe and effective minimally-invasive treatment for advanced acetabular metastases.

Key words: Microwave ablation, Polymethyl methacrylic, Acetabular metastases, Clinical efficacy