Abstract: Objective To analyze the distribution characteristics and the causes of hospitalized death cases with malignant tumors in a tertiary hospital, and to provide the reference for hospital management and discipline construction. Methods Based on the clinical information data of 1, 834 hospitalized death cases with malignant tumors in Guangxi Medical University Cancer Hospital from January 1, 2010 to December 31, 2020, the trend of fatality rate, gender and age distribution, and the rank of death in malignant tumors were analyzed.  Results The fatality rate of hospitalized patients with malignant tumors showed a decreasing trend, with higher fatality rate in male than in female (χ²=141.487, P<0.001). The fatality rate of hospitalized patients with malignancies in different age groups was statistically significant  (χ²=389.637, P<0.001) and increased with age. The top 10 cancer causes of death were lung cancer, liver cancer, colorectal cancer, breast cancer, gastric cancer, lymphoma, oesophageal cancer, nasopharyngeal cancer, ovarian cancer, and pancreatic cancer. Conclusions  The fatality rate of hospitalized patients with malignant tumors decrease gradually; lung cancer and liver cancer are the main causes of death diseases. Hospitals need to further optimize the allocation of medical resources, and strengthen the construction of corresponding disciplines, continuously improving the quality of medical treatment and reducing the fatality rate of tumors.

Key words: Malignant tumor；Hospitalized patient；Cases of death；Sequence of death cause ')">">Malignant tumor；Hospitalized patient；Cases of death；Sequence of death cause ,