Abstract: Objective To investigate the clinical efficacy of percutaneous vertebroplasty(PVP) combined with posterior decompression in the treatment of multiple jumping spinal metastasis tumor patients. Methods The clinical data of 96 patients with multiple jumping spinal metastasis tumor admitted to our hospital from January 2013 to December 2019 were collected, and intraoperative blood loss, the VAS score, KPS score and ASIA nerve injury grading before and after surgery were observed. Results A total of 96 patients were successfully completed PVP combined with posterior decompression therapy. The VAS score was decreased at 1 month after surgery ［(1.0±0.6) points vs (8.5±1.8) points, P<0.001)］, and the KPS score was increased at 3 months after surgery ［(75.0±18.2) points vs (45.0±10.5) points, P<0.001)］. One month after surgery, the ASIA grades of 87.5% patients were improved, and the proportion of patients with grade D and E were increased from 11.4% and 0% to 40.6% and 29.2%, respectively. Conclusion The treatment of percutaneous vertebroplasty combined with posterior decompression in multiple jumping spinal metastasis tumor patients can significantly relieve pain, improve quality of life, effectively relieve the spinal cord and restore damaged nerve function to various degree.

Key words: Spinal metastasis, Percutaneous vertebroplasty, Posterior decompression, Spinal cord injury