| 1Muraoka S,Miura T.Free radicals mediate cardiac toxicity induced by adriamycin[J].Yakugaru Zasshi,2003,123(10):855-866.
2Myers C.The role of iron in doxorubicin induced cardiomyopathy[J].Semin On-col,1998,25(4-10):10-14.
3Floyd JD,Nguyen DT,Lobins RL.Cardiotoxicity of cancer therapy[J].J Clin On-col,2005,23(30):7685-7696.
4Kim SY,KimSJ,KimBJ,eta1.Doxorubicin induced reactive oxygeny species gen-eration and intraceUular Ca2+increase are reciprocally-modulated in rat eardio-myocytes[J].Exp Mol Med,2006,38(5):535-545.
5Wallace KB.Adriamycin-induced interference with cardiac mitochondrial calcium homeostasis[J].Cardiovasc Toxicol,2007,7(2):101-107.
6Kalyanaraman B,Joseph J,Kalvendi S,et al.Doxorubicin-induced apoptosis:impli-cation in cardiotoxicity[J].Mol Cell Biochem,2002,234-235(1):119-124.
7Shi J,Wei L.Rho kinase in the regulation of cell death and survival[J].Arch Im-munol Ther Exp,2007,55(2):61-75.
8Gilleron M,Marechal X,Montaigne D,et al.NADPH oxidases participate to doxo-rubicin-induced cardiac myocyte apoptosis[J].Biochem Biophys Res Commun,2009,388(4):27-31.
9Bernuzzi F,Recalcati S,Alberghini A,et al.Reactive oxygen species-independent apoptosis in doxorubicin-treated H9c2cardiomyocytes:role for heme oxygenase-1downmodulation[J].Chem Biol Interact,2009,177(1):12-20.
10Zhou S,Starkov A,Froberg MK,et al.Cumulative and irreversible cardiac mito-chondrial dysfunction induced by doxorubicin[J].Cancer Res,2001,61(2):771-777.
11Lebrecht D,Walker UA.Role of mtDNA lesions in anthracycline Cardiotoxicity[J].Cardiovasc Toxicol,2007,7(2):108-113.
12Gianni L,Herman EH,Lipshultz SE,et al.Anthracycline cardiotoxicity:from bench to bedside[J].J Clin Oncol,2008,26(22):3777-3784.
13Conklin KA.Coenzyme Q10for prevention of anthracycline—induced Cardiotoxici-ty[J].Cs/lcer Ther,2005,4(2):110-130.
14Franco R,Schoneveld OJ,Pappa A,et a1.The central role of glutathione in the pathophysio1ogy of human diseases[J].Arch Physiol Biochern,2007,113(4-5):234-258.
15Kaiserova H,Simunek T,van der Vijgh WJ,eta1.Flavonoids as protectors against doxorubicin cardiotoxicity:role of iron chelation,antioxidant activity and inhibi-tion of carbonyl reductase[J].Biochim Biophys Acta,2007,1772(9):1065-1074.
16Bruynzeel AM,Niessen HW,Bronzwaer JG,eta1.The effectof monohydroxyethyl-rutoside on doxorubicin-induced cardiotoxicity in patients treated for metastatic cancer in a phase II study[J].Br J Cancer,2007,979(8):1084-1089.
17Liu X,Chen Z,Chua CC,et al.Melatonin as an effective protector against doxoru-bicin-induced cardiotoxicity[J].Am J Physiol Heart Circ Physiol,2002,283(1):254-263.
18Kaiserova,H,Simunek,T,van der Vijgh,,et al.Flavonoids as protectors against doxorubicin cardiotoxicity:Role of iron chelation,antioxidant activity and inhibi-tion of carbonyl reductase[J].Bio-chim Biophys Acta,2007,1772(9):1065-1074.
19Koukourakle MI.Amifostine in clinical oncology:current use and future applica-tions[J].Anticancer Drugs,2002,13(3):181-209.
20Stolarska M,Mlynarski W,Zalewska-Szewczyk,B,et al.Cytoprotective effect of amifostine in the treatment of childhood neoplastic diseases-a clinical study in-cluding the pharmacoeconomic analysis[J].Pharmacol Rep,2006,58(1):30-34.
21Hensley ML,Hagerty KL,Kewalramani T,et al.American Society of Clinical On-cology2008clinical practice guideline update:use of chemotherapy and radiation therapy protectants[J].J Clin Oncol,2009,27(1):127-145.
22Cvetkovi RS,ScottLJ.Dexrazoxane:a reviewof its use for cardioprotection during anthracycline chemotherapy[J].Drugs,2005,65(7):1005-1024.
23Tatlidede E,Sehirli O,Velioglu A,et al.Resveratrol treatment protects against doxorubicin-induced cardiotoxicity by alleviating oxidative damage[J].Free Radical Research,2009,43(3):195-205.
24邱超学,张琴琴.门冬氨酸钾镁防治阿霉素急性心脏毒性30例[J].实用医学杂志,2006,22(22):2671-2672.
25Machado V,Cabral A,Monteiro P,et al.Carvedilol as a protector against the car-diotoxicity induced by anthracyclines[J].Rev Port Cardiol,2008,27(10):1277-1296.
26Kang YJ.Antioxidant defense against anthracycline cardiotoxicity by metallothio-nein[J].Cardiovascular Toxicology,2007,7(2):95-100.
27Kim KH,Oudit GY,Backx PH.Erythropoietin protects against doxorubicin—in-duced cardiomyopathy via a PI3K—dependent pathway[J].J Pharmacol Exp T-her,2008,324(1):160-169.
28Hiraumi Y,Iwai-Kanai E,Baba S,etal.Granulocyte colony-stimulatingfactor pro-tects cardiac mitochondria in the early phase of cardiac injury[J].Heart Circ Physiol,2009,296(3):823-832.
29Emanuelov AK,Shainberg A,Chepurko Y,et al.Adenosine A3receptor-mediated cardioprotection against doxorubicin-induced mitochondrial damage[J].Bio-chemical Pharmacology,2009,79(2):180-187.
30陈小非.万爽力对阿霉素化疗后大鼠围麻醉期心肌肌钙蛋白Ⅰ影响的实验研究[D].广西医科大学,2007.
31李生,华茜.曲美他嗪治疗阿霉素心脏毒性致室性心律失常的临床研究[J].中国社区医师,2007,9(20):23.
32Kelishomi RB,Ejtemaeemehr S,Tavangar SM,et a1.Morphine is protective a-gainst doxorubicin.induced cardiotoxicity in rat[J].Toxicology,2008,243(1-2):96-104.
33王瑞芹,解英,赵素珍.生脉注射液防治阿霉素相关性心脏毒性的临床观察[J].中西医结合心脑血管病,2006,4(12):1092-1093.
34李玉芹.黄芪注射液治疗阿霉素致乳腺癌心肌损害的临床观察[J].黑龙江医药科学,2008,31(5):37-38.
35刘晓健,刘义,钟彩霞.参脉注射液对阿霉素损伤心肌细胞的保护作用[J].中国医疗前沿,2009,4(3):7-8.
36Li L,Pan Q,Han W,et a1.Schisandrin b prevents doxorubicin—induced cardio-toxicity via enhancing gutathione redoxcycling[J].Cancer Res,2007,13(22):6753-6760.
37JiangB,ZhangL,WangY,etal.Tanshinone IIAsodiumsulfonate protects against cardiotoxicity induced by doxorubicin in vitro and in vivo[J].Food and Chemical Toxicology,2009,47(7):1538-1544. |
