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中国癌症防治杂志

中国癌症防治杂志

• 论文 • 上一篇    下一篇

320例老年肺癌电子支气管镜检查的临床分析

王鹏;   

  1. 解放军总医院南楼临床部呼吸内科;
  • 收稿日期:2010-09-25 修回日期:2010-09-25 出版日期:2010-09-25 发布日期:2010-09-25

Clinical analysis of electronic bronchoscope on 320 cases of elderly patient with lung cancer

WANG Peng   

  1. (Respiratory Department, South Building, General Hospital of PLA, Beijing 100853,China
  • Received:2010-09-25 Revised:2010-09-25 Online:2010-09-25 Published:2010-09-25

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被引次数

2

摘要： 目的探讨老年肺癌患者电子支气管镜下的特点,分析组织学类型与性别、镜下形态及病变部位的关系。方法回顾性分析320例经电子支气管镜确诊肺癌的年龄≥65岁的患者。结果 320例肺癌患者中,中央型肺癌199例(62.2%),外周型肺癌121例(37.8%)。病理类型最常见鳞癌176例(55.0%),其次是腺癌80例(25.0%),小细胞癌53例(16.6%)。镜下表现:增殖型162例(50.6%),肿块伴浸润型85例(26.6%),管壁浸润型66例(20.6%),外压型7例(2.2%)。男性鳞癌患病率显著高于女性(P=0.0000),而女性腺癌与小细胞癌患病率显著高于男性(P=0.0033,0.0035)。4种镜下表现与不同病理类型之间差异有统计学意义(P=0.0000)。在鳞癌、小细胞癌中,中央型肺癌发生率显著高于周围型肺癌(P=0.0476,0.0245)。在腺癌中,周围型肺癌发生率显著高于中央型肺癌(P=0.0000)。结论老年肺癌以中央型肺癌多见,鳞癌和腺癌发生率较高,镜下表现以增殖型多见。电子支气管镜操作方便,患者耐受性较好,对老年肺癌患者的诊断具有重要意义。

关键词: 肺肿瘤, 支气管镜

Abstract: Objective To analyze the feature of electronic bronchoscope on elderly patient with lung cancer, and to investigate the correlation among the histopathologic type of lung cancer, gender and the feature under bronchoscope.Methods320 patients with lung cancer older than 65 years were observed with electronic bronchoscope.ResultsAmong the 320 patients, cases of the central bronchogenic and the peripheral were 199 (62.2%) and 121 (37.8%) respectively. The most common histopathologic type was squamous cell cancer which had totally 176 (55.0%) cases. The percentage of adenocarcinoma and small cell lung cancer was 25.0% and 16.6% respectively. Under electronic bronchoscope, the cases of proliferation type were 162 (50.1%), mixed type 85 (26.6%), infiltration type 66 (20.1%) and outside oppression type 7 (2.2%). Among the patients with squamous cell cancer, male was significantly more than female (P=0.0000). While among the adenocarcinoma and small cell lung cancer, female was significantly more than male (P=0.0476 and P=0.0245 respectively). The feature under the electronic bronchoscope was significantly related to histopathologic type (P=0.0000). Among the cases of squamous cell cancer and small cell lung cancer, the cases of central bronchogenic cancer were significantly more than that of peripheral cancer (P=0.0476 and P=0.0245 respectively). Among the cases with adenocarcinoma, the cases of peripheral cancer were significantly more than that of central bronchogenic cancer (P=0.0000).ConclusionsCentral bronchogenic cancer, squamous cell cancer and adenocarcinoma are the common types among the elderly patients with lung cancer, and proliferation is the most common feature under bronchoscope. Electronic bronchoscope play an important role in diagnosis of lung cancer, for it is simple to operate and is well to be tolerated.

Key words: Lung cancer, Electronic bronchoscope, Elder