关键词: 结直肠癌, 高危, 筛查, 肠镜检查

Abstract: Objective To analyze the screening results of early diagnosis and treatment program for colorectal cancer in rural areas of Fengtai district, Beijing from 2015 to 2022. Methods The permanent residents aged 40 to 74 years old in rural early cancer diagnosis and early treatment project sites in Fengtai district, Beijing from 2015 to 2022 were selected for screening. The high risk population of colorectal cancer were initially screened through questionnaire survey and fecal immunochemical test, and colorectal colonoscopy was performed. The high risk rate, colonoscopy compliance rate and detection rate of colorectal cancer were calculated. Results A total of 14,972 residents in Fengtai district participated in high risk assessment of colorectal cancer, of which 5,961 people were found to be at high risk of colorectal cancer, with a high risk rate of 39.81%. The high risk rate of males was lower than females (P<0.001), the highest was in the 70-74 age group (43.53%) and the lowest was in the 40-44 age group (31.88%). Colonoscopy was performed in 3,314 cases, with the compliance rate of 55.59%, the highest was in the 45-49 age group (63.23%) and the lowest was in the 65-69 age group (48.58%). Among the colonoscopy results, the detection rate of abnormal lesions was 5.07%, among which the detection rates of advanced adenoma, other lesions with moderate or severe dysplasia, early cancer, and advanced cancer were 4.77%, 0.09%, 0.15%, and 0.06%, respectively. The detection rates of advanced adenoma, early cancer, and advanced cancer in males are higher than those in females, while the detection rates of other lesions with moderate or severe dysplasia was lower than those in females. There was a statistically significant difference in the detection rate of advanced adenoma among different age groups (P<0.001), and the detection rate was highest in the 70-74 age group (9.57%). Conclusions The high risk rate of colorectal cancer screening in rural areas of Fengtai district, Beijing is relatively high, and females have a higher risk than males, and the elderly is the high risk population. In the future, it is necessary to strengthen the detection and screening of these high risk population, and improve their compliance. 

Key words: Colorectal cancer, High risk, Screening, Colonoscopy