1Jin BQ,Adhensive M[A].In:Jin BQ.Cellular and molecular immunology[M].2nd ed.Beijing:Kexue Chubanshe(Science Publishing House),2001:34-88.
2Bilato C,Curto KA,Monticone RE,et a1.The inhibition of vascular smooth muscle cell migration by peptide and antibody antagonists of the alpha v beta3integrin complex is reversed by activated calcium/calmodulin-dependent protein kinaseⅡ[J].J Clin Investi,1997,100:693-704.
3Wu X,Mogford JE,Platts SH,et a1.Modulation of calcium current in arteriolar smooth muscle by alpha v beta3and alpha5beta1integrin ligands[J].J Cell Bi-ol,1998,143:241-252.
4Horton MA.Theανβ3integrin“ventronectin receptor”[J].Int J Biochem Cell Bi-ol,l997,29(5):72l-725.
5Clark RA,Tonnesen MG,Gailit J,et a1.Transient function expression ofανβ3on vascular cells during wound repair[J].Am J Pathol,1996,148(5):1407-21.
6Sheu JR,Yen MH,Kan YC,et a1.Inhibition of angiogenesis in vitro and in vivo:Comparison of the relative activities of triflavin,an Arg-Gly-Asp-containing pep-tide snd snti-ανβ3integrin monoclonal antibody[J].Boichem Biophys Acta,1997,l336(3):445.
7牟丹蕾,白雪帆,李光玉,等.人整合素β3亚基真核表达载体的构建及表达[J].中国病毒学,2003,18:5-8.
8刘亮,刘畅,张晓启,等.巨噬细胞对内皮细胞系同源盒B2基因和血管内皮生长因子受体mRNA及整合素ανβ3表达的影响[J].中华烧伤杂志,2005,21:199-202.
9刘亮,刘旭盛,张晓启,等.巨噬细胞对血管内皮细胞增殖、Hoxb2、血管内皮生长因子受体和整合素ανβ3表达的影响[J].第一军医大学学报,2005,25:148-151.
10Cowden KD,Dahl SE,Robertson VM et al.Hypoxia-inducible factor regulatesανβ3integrin cell surface expression[J].Molecular Biology of the Cell,2005,16,1901-12.
11蔡强,叶应湖,王国安,等.血管内皮生长因子在人脑胶质瘤侵袭中的作用[J].肿瘤防治研究,2002,29(6):447-449.
12Bello L,Francolini M,Marthyn P,et a1.ανβ3andανβ5integrin expression in gli-oma periphery[J].Neurosurgery,2001,49(2):380-390.
13艾文兵,陶胜忠,薛德麟,等.人脑胶质瘤中VEGF和整合素ανβ3的表达及相关性研究[J].肿瘤防治研究,2005,32(2):70-72.
14Xie D,Yin D,TongX,etal.Cyr61is overexpressed in gliomas and involved in in-tegrin-linked kinase-mediated Akt and beta-catenin-TCF/Lef signaling pathways[J].Cancer Res,2004,64(6):1987-96.
15Schmieder AH,Winter PM,Caruthers SD,et al.Molecular MRI imaging of mela-noma angiogenesis with alphanubeta3-targeted paramagnetic nanoparticles[J].Magn Reson Med,2005,53(3):621-627.
16Lijowski M,Caruthers S,Hu G,etal.High sensitivity:high-resolution SPECT-CT/MR molecular imaging of angiogenesis in the Vx2model[J].Invest Radiol,2008,Oct2.[Epub ahead of print].
17Angelikavon W,Arsten H,Michael Z,et al.In vivo imaging of integrinανβ3ex-pression using fluorescence-mediated tomography[J].Eur J Nucl Med Mol Ima-ging(2007)34:745-754.
18Murphy EA,Majeti BK,Barnes LA,et al.Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis[J].Proc Natl Acad Sci USA,2008,105(27):9343-48.
19Kim WJ,Yockman JW,Lee M,et al.Soluble Flt-1gene delivery using PEI-g-PEG-RGD conjugate for anti-angiogenesis[J].J Control Release,2005,106(1-2):224-234.
20Silletti S,Kessler T,Goldberg J,et al.Disruption of matrix metallo-proteinase2binding to integrin alpha v beta3by an organic molecule inhibits angiogenesis and tumor growth in vivo[J].Proc Natl Acad Sci USA,2001,98(1):119-124.
21王臣,侯利华,张彦明等.抗人整合素ανβ3单链抗体的构建和表达[J].细胞与分子免疫学杂志,2004,20(2):159-162.
22王臣,侯利华,张彦明,等.抗人整合素ανβ3单抗E10鼠/人嵌合Fab噬菌体抗体的构建和表达[J].西北农林科技大学学报(自然科学版),2004,32(5):9-13.
23王臣,侯利华,杜桂鑫,等.构建预设CDR3基因噬菌体抗体库筛选抗人整合素ανβ3mAb的人源化Fab[J].细胞与分子免疫学杂志,2006,22(1):64-67.
24Trikha M,Zhou Z,Nemeth JA,etal.CNTO95,a fully human monoclonal antibod-y that inhibitsανintegrins,has antitumor and antiangiogenic activity in vivo[J].Int J Cancer,2004,110:326-335.
25贾欣永,李杰,徐宗珍,等.整合素ανβ3反义基因抑制裸鼠种植性肝癌血管生成的实验研究[J].中国现代普通外科进展,2007,10(2):153-155. |