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中国癌症防治杂志

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原发性肝癌切除术后胸水成因的临床研究

袁卫平;谭新华;   

  1. 广西医科大学肿瘤医院肝胆外科;
  • 收稿日期:2009-06-25 修回日期:2009-06-25 出版日期:2009-06-25 发布日期:2009-06-25

Clinical research on cause of pleural fluid after hepatectomy

YUAN Wei-ping,TAN Xin-hua.   

  1. (Department of Hepatobiliary Surgery,Affiliated Tumor Hospital of Guangxi Medical University, Nanning Guangxi 530021,China
  • Received:2009-06-25 Revised:2009-06-25 Online:2009-06-25 Published:2009-06-25

摘要: 目的探讨原发性肝癌切除术后胸水发生的成因。方法选取手术切除的原发性肝癌病人133例为对象进行回顾性研究。结果133例病人中有69例出现胸水。胸水组(G1组)中行右肝手术尤其是行右三角韧带及右冠状韧带分离者比例明显高于无胸水组(G2组),且术后并发腹水量较高。无胸水组术后肝功能明显好于胸水组。术前肝功能、术中出血量、肝门阻断时间、肿瘤大小等两组间比较差异无统计学意义。结论肝切除术后并发胸水,主要和手术部位、术后肝功能及肝周韧带分离有关。肝切除对右肝韧带的游离和膈肌损伤是导致术后胸水发生的主要原因。在围手术期维持良好肝功能的前提下,术中仔细分离肝周韧带,减少膈肌的损伤,可能有助于减少术后胸水的发生。

关键词: 原发性肝癌, 胸水

Abstract: Objective To investigate the causes of pleural effusion after hepatectomy.Methods 133 cases of primary hepatic carcinoma(PHC) underwent hepatectomy were enrolled in this retrospective study.Results Pleural effusion emerged in 69 cases after hepatectomy.The ratio of cases underwent right hepatectomy especially with dissection of triangulare ligamentum and coronary ligament in pleural effusion group(group G1) was significantly higher than that in no-pleural effusion group(group G2). The volume of effusion after operation in group G1 was larger than that in group G2.The postoperative hepatic function was much better in group G2 than that in group G1.There was no statistically significant different between the two groups concerning the factors such as preoperative hepatic function,volume of bleeding,obstructive time of portal vein and size of tumor.Conclusions Complicated pleural effusion after hepatectomy is mainly related to operative site,postoperative hepatic function and dissection of peri-hepatic ligaments.The main causes of pleural effusion are the dissection of right hepatic ligaments and damage of diaphragm during operation.Maintenance of fine hepatic function before and after operation,careful dissection of peri-hepatic ligaments and avoiding damage on diaphragm may help to reduce the incidence of postoperative pleural effusion.

Key words: Primary hepatic carcinoma(PHC), Pleural effusion