1王树声,苏建家,冯百芳,等.乙型肝炎动物模型的研究[J].医学研究通讯, 2001.30:7-10.
2苏建家,严瑞琪,甘友全,等.成年树鼩实验感染人乙型肝炎病毒的研究[J].中华肝脏病杂志,1987,16:103-105.
3张晶晶,岳惠芬,苏建家.HBx、ras基因的克隆及睾丸注射法制备转基因小鼠、树鼩的研究[J].药学学报,2007,42(suppl):35-36.
4 Gordon JW.Scangos GA,Plotkin DJ,et al.Genetic transformation of mouse embryos by microinjection of purified DNA[J].Proc Natl Acad Sci USA,1980,77(12): 7380-84.
5 Herzig M,Christofori G.Recent advances in cancer research:mouse models of tumorigenesis [J].Biochim Biophys Acta,2002,1602(2):97-113.
6 Wang Y,Wang H.Functional genomics in drug target research[J].Chin Pharmacol Bull,2005,21(3):266-268.
7吴云,徐容,曹广文,等.腺病毒介导mIFN2β基因转染的小鼠黑色素瘤细胞体内致瘤性及抗肿瘤作用的实验研究[J].中国药理学通报,2004,20 (6):677-680.
8 Kioke K.Hepatocarcinogenesis in hepatitis viral infection:lessons from transgenic mouse studies[J].J Gastroenterol,2002,37 Suppl 13:55-64.
9 Yu DY,Moon HB,Son JK,et al.Incidence of hepatocelhikw carcinoma in transgenic mice expressing the hepatitis B virus X-protein[J].J Hepatol,1999,31(1): 123-132.
10 Farza H,Hadchouel M,Scotto J,et al.Replication and gene expression of hepatitis B virus in a transgenic mouse that contains the complete viral genome.[J].J Virol, 1988,62(11):4144-52.
11李厚达,李劲松,陈建全,等.复制型HBV转基因小鼠的遗传与繁育研究[J].中国实验动物学报,1996,4(2):71-76.
12 Nakamoto Y.Guidotti L G,Kuhlen CV,et al.Immune pathogenesis of hepatocellular carcinoma[J].J Exp Med,1998,188(2):341-350.
13 Hingorani SR,Petricoin EF,Maitra A,et al.Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse[J],Cancer Cell,2003,4:437- 450.
14 Ijichi H,Chytil A,Gorska A E,et al.Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas specific blockade of transforming growth factor signaling in cooperation with active Kras expression[J].Genes Dev,2006,20: 3147-60.
15张晶晶,岳惠芬,曹骥,等.HBx、ras基因的克隆及精原细胞转染法制备转基因小鼠的初步研究[J].现代生物医学进展,2006,8(2):205-208.
16 Graur D,Duret L,Gouy M.Phylogenetic position of the order Lagomorpha(rabbits, hares and allies)[J].Nature,1996,379(6 563):333-335.
17 Knight KL,Spieker-Polet H,Kazdin DS,et al.Transgenic rabbits with lymphocytic leukemia induced by the c-myconcogene fused with the immunoglobulin heavy chainenhancer[J].Proc Natl Acad Sci USA,1988,85(9):3130-34.
18 Peng X,Olson RO,Christian CB,et al.Papillomas and carcinomas in transgenic rabbits carrying EJ-ras DNA and cottontail rabbit papillomavirus DNA[J].J Virol, 1993,67(3):1698-1701.
19 Sethupathi P,Spieker-Polet H,Polet H,et al.Lymphoid and non-lym phoid tumors in E kappamyc transgenic rabbits[J].Leukemia,1994,8(12):2144-55.
20 Peng X,Griffith JW,Han R,et al.Development of keratoacanthomas and squamous cell carcinomas in transgenic c rabbits with targeted expression of EJras oncogene in epidermis[J].Am J Pathol,1999,155(1):315-324.
21 Peng X,Gfiffith JW,Lang CM.Reinitiated expresion of EJras transgene in targeted epidermal cells of transgenic rabbits by cottontail rabbit papilomavirus infection [J].Cancer Lett,2001,171(2):193-200.
22 Sato M,Ishikawa A,Kimura M.Direct injection of foreign DNA into mouse testis as a possible in vivo gene transfer system via epididymal spermatozoa[J].Mol Reprod Dev,2002,61:49-56.
23 Lavitrano M,Forni M,Bacci ML,et al.Sperm mediated gene transfer in pig:Selection of donor boars and optimization of DNA uptake[J].Mol Reprod Dev, 2003,64:284-291. |