Abstract: Objective To investigate the pregnancy status of patients with malignant ovarian germ cell tumors (MOGCT) after fertility sparing treatment and its influencing factors. Methods A total of 72 MOGCT patients, who were admitted to the Guangxi Medical University Cancer Hospital and received fertility sparing treatment from December 2006 to March 2019, were selected as the research subjects. According to the pregnancy status after treatment, the patients were divided into pregnancy group and infertility group. The logistic regression was used to analyze the factors influencing pregnancy. Results  The pregnancy rate of 72 patients was 66.7%. The logistic regression results showed that lymph node removal, wedge removal of the contralateral ovary, and omentum removal were independent influence factors of pregnancy (all P<0.05). Conclusions The pregnancy rate of MOGCT patients with wedge removal of the contralateral ovary, lymph node removal and omentum removal was reduced after fertility sparing treatment, but the conclusion needs further confirmation.

Key words: Malignant ovarian germ cell tumors, Fertility sparing treatment, Fertility