Abstract: Objective To analyze the situation and distribution of cervical human papillomavirus (HPV) infection among women in Nanning area of Guangxi. Methods Through clinic opportunistic screening，1 250 women received HPV genotypes test with gene chip technology. Result The positive rate of HPV DNA was 31.36%(392/1250).The major infected subtypes were the low-risk ones，and the descending order of prevalence was subtype 6，11 and 43. The descending order of prevalence among the high-risk subtypes was 16，58，52 and 18. Single high-risk subtype infection was common，followed by single low-risk subtype infection.Among the multiple-subtype infections，double infection with low-and high-risk subtype was common，while triple or quadruple infection was rare.Women aged ≤25 years old accounted for 42.35% of infection，followed by 25 to 34 years old. Conclusions Distribution of HPV subtypes is regional. Detection of HPV subtypes will help to predict the outcome of infection，guide clinical treatment and follow-up.

Key words: Cervix neoplasms, Human papillomavirus, Genotype