Abstract: Objective To estimate the incidence and mortality of nasopharyngeal carcinoma in Henan Province in 2016 based on the cancer registration data. Methods The data quality was assessed, which included completeness, validity, and reliability according to the criteria of Guideline on Cancer Registration in China and IARC/IACR. Based on the population data of Henan Province in 2016, the incidence and mortality of nasopharyngeal carcinoma in Henan Province were estimated by urban /rural areas and gender. The age-standardized rates by Chinese standard population (ASRC) was calculated according to the Chinese standard population in 2000 and the age-standardized rates by world standard population (ASRW) was calculated according to the Segi's population. Results In 2016, there were 1, 197 new cases of nasopharyngeal carcinoma in Henan Province, with an incidence of 1.11/10⁵, with ASRC of 0.89/10⁵ and ASRW of 0.85/10⁵. The male to female incidence ratio was 1.93∶1. The incidences of nasopharyngeal carcinoma in urban and rural areas were 0.83/105 and 0.92/10⁵, respectively. In 2016, there were 770 cases of death from nasopharyngeal cancer in Henan Province, with a mortality rate of 0.71/10⁵, with ASRC of 0.56/10⁵ and ASRW of 0.54/10⁵. The male to female mortality ratio was 2.36:1. The mortality rates of nasopharyngeal carcinoma in urban and rural areas was 0.52/10⁵ and 0.57/105, respectively. The cumulative incidence and mortality rates (0-74 years old) were 0.09% and 0.06%, respectively. Conclusions The disease burden of nasopharyngeal carcinoma in Henan Province is lower than that of Chinese average level, and males are the key population for prevention and control. The effective prevention and control measures should be established according to the epidemic characteristics of nasopharyngeal carcinoma in Henan Province in the future.

Key words: Nasopharyngeal carcinoma, Incidence, Mortality, ')">Henan Province