微信公众号

官网二维码
中国癌症防治杂志

中国癌症防治杂志 ›› 2022, Vol. 14 ›› Issue (3): 301-305.doi: 10.3969/j.issn.1674-5671.2022.03.09

• 临床研究 • 上一篇    下一篇

锥光束乳腺CT体积测量在乳腺癌保留乳头乳晕乳房切除术后假体乳房重建手术中的应用

  

  1. 广西医科大学附属肿瘤医院乳腺外科；广西临床重点专科（医学影像科），广西医科大学附属肿瘤医院优势培育学科（医学影像科）
  • 出版日期:2022-06-25 发布日期:2022-06-30
  • 通讯作者: 刘剑仑 E-mail：2301881346@qq.com
  • 基金资助:
    国家重点研发计划项目（2017YFC0112600；2017YFC0112603）；广西影像医学临床医学研究中心建设项目（桂科AD20238096）

Application of cone-beam breast CT volume measurement in prosthetic breast reconstruction after nipple-sparing mastectomy in breast cancer 

  • Online:2022-06-25 Published:2022-06-30

PDF (PC)

157

赞

摘要： 目的 探讨锥光束乳腺CT（cone-bean breast computed tomography，CBBCT）在保留乳头乳晕乳房切除（nipple-sparing mastectomy，NSM）术后假体乳房重建手术中的应用价值。方法 选择2020年7月1日至2022年1月31日于广西医科大学附属肿瘤医院乳腺外科接受NSM术后假体乳房重建的52例乳腺癌患者为研究对象，采用Spearman秩相关分析患侧乳腺和对侧乳房CBBCT测量的体积与临床手工线性测量法测量的置入假体体积之间的相关性，建立简单线性回归方程预测CBBCT推算的假体体积，并比较其与置入假体体积的差异。采用Harris美容评分标准评价术后3个月的美容效果。结果 所有患者均完成假体乳房重建术，未出现假体破裂、假体移位等并发症。患侧乳腺CBBCT测量体积、对侧乳房CBBCT测量体积均与置入假体体积相关（rs=0.73，0.81）。基于对侧乳房CBBCT测量体积构建线性预测模型y=0.001x+4.897（R2=0.7，P<0.001），临床验证显示，模型预测的假体体积与放置假体体积差异无统计学意义（t=0.03， P=0.98），平均绝对误差值为0.1 cm3；Harris美容评分结果显示，术后3个月美容效果优4例，良6例。结论 在NSM术后假体乳房重建手术中CBBCT可有效预测放置假体的体积。

关键词:  , 乳腺癌；保留乳头乳晕乳房切除术；假体乳房重建术；锥光束CT；乳房体积；假体测量

Abstract: Objective To investigate the application value of cone-beam breast computed tomography (CBBCT) in prosthetic breast reconstruction after nipple-sparing mastectomy (NSM). Methods A total of 52 breast cancer patients who received prosthetic breast reconstruction after NSM at Guangxi Medical University Cancer Hospital from July 1, 2020 to January 31, 2022 were selected as the subjects. Spearman rank correlation was used to analyze the correlation between the measured volumes of the affected breast CBBCT and the contralateral breast CBBCT and the implanted prosthesis volume obtained by the clinical manual linear measurement method. A simple linear regression equation was established to predict the prosthesis volume calculated by CBBCT, and to compare it with the volume of implanted prosthesis. The Harris beauty score was used to evaluate the cosmetic effect 3 months after surgery. Results All patients completed breast prosthesis reconstruction without prosthesis rupture, prosthesis displacement and other complications. The measured volumes of the affected breast CBBCT and the contralateral breast CBBCT were correlated with the implanted prosthesis volume (rs=0.73, 0.81). A linear prediction model y=0.001x+4.897 (R2=0.7, P<0.001) was constructed based on the measured volume of the contralateral breast CBBCT. The clinical validation showed that there was no significant difference between the model predicted volume and the implanted volume of prosthesis (t=0.03, P=0.98), and the mean absolute error value was only 0.1 cm3. The Harris beauty score showed that the cosmetic effect was excellent in 4 cases and good in 6 cases 3 months after operation. Conclusions CBBCT can effectively predict the volume of implanted prosthesis in breast reconstruction surgery after NSM.

Key words: Breast cancer, NSM, Prosthetic breast reconstruction, CBBCT, Breast volume, Prosthesis measurement

中图分类号: 

  •