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中国癌症防治杂志

中国癌症防治杂志 ›› 2017, Vol. 9 ›› Issue (1): 61-64.doi: 10.3969/j.issn.1674-5671.2017.01.12

• 临床研究 • 上一篇    下一篇

CT-MRI图像融合技术在脑胶质瘤术后放疗靶区勾画中的应用

  

  1. 广东省梅州市人民医院
  • 出版日期:2017-02-25 发布日期:2017-03-24

Application of CT-MRI fusion images for determining the target region in postoperative glioma

  1. Meizhou People's Hospital
  • Online:2017-02-25 Published:2017-03-24

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被引次数

4

摘要：

目的 探讨CT-MRI图像融合技术在脑胶质瘤术后调强适形放疗靶区勾画中的临床应用价值。方法 由2位不同资历的肿瘤放疗专科医师分别在10例脑胶质瘤患者术后的CT定位图像、CT-MRI融合图像上勾画临床靶区（clinical target volume，CTV），并比较组间勾画体积差异。结果 住院医师组与副主任医师组勾画的CTVCT体积均比CTVCT+MRI体积大，差异有统计学意义（P﹤0.05），住院医师组勾画的CTVCT体积大于副主任医师组，差异有统计学意义（P﹤0.05），两组医师勾画的CTVCT+MRI体积差异无统计学意义（P＞0.05）。结论 CT-MRI图像融合技术能够明显提高脑胶质瘤术后放疗靶区勾画的准确性，减少主观因素差异性。

关键词: 颅内肿瘤, 脑胶质瘤, 术后放疗, 临床靶区, 图像融合

Abstract:

Objective To investigate the application of computed tomography（CT） and magnetic resonance imaging （MRI） fuse images for determining the target region in postoperative glioma. Methods CT and MRI images were fused from 10 patients. The CTV of each patient was independently determined by an associate chief doctor and a resident based on CT and MRI images. The CTV contoured on CT （CTVCT） and MRI （CTVMRI） were measured，and composite volumes （CTVCT+MRI） were calculating as the sum of CT-defined CTV and MRI-defined CTV. Differences between these volumes were compared. Results Volumes of CTVCT+MRI were larger than the volumes of CTVCT（P<0.05） determined by all doctors. Volumes of CTVCT determined by associate chief doctors was larger than that（P<0.05） determined by resident doctors. Volumes of CTVCT+MRIdid not differ significantly between associate chief doctors and residents（P>0.05）. Conclusions CT-MRI fusion images can significantly improve accuracy in radiation therapy after glioma surgery.The composite volume （CTVCT+MRI） may be less dependent on physician experience.

Key words: Intracranial neoplasms, Glioma, Postoperation radiotherapy, Clinical target volume, Image fusion