Abstract:

Objective Analyze incidence of liver cancer and associated mortality in Guangxi in 2013 based on areas with cancer registry reporting. Methods In 2016，8 cancer registries of Guangxi reported cancer data for 2013，and 6 registries were found to conform to data quality criteria of the NCCR.Data from these 6 registries were analyzed to determine incidence and mortality of liver cancer stratified by areas（urban/rural），sex，age group and region.Proportions，cumulative incidence/mortality rates，and truncated incidence/mortality rates were calculated.The Chinese population census in 2000 and Segi's population were used for age-standardized incidence/mortality rates. Results All 6 cancer registries covered a total population of 5，196 ，871（1，933，143 in urban areas，3，263，728 in rural areas）.The total number of new cases of liver cancer was 2，165，and the number of liver cancer-related deaths was 1，801.Morphology-verified cases accounted for 21.02%.Death certifications accounted for 2.54%. The ratio of mortality to incidence was 0.83.The crude incidence of liver cancer in China cancer registration areas was 41.66/10⁵（males 64.07/10⁵，females 17.42/10⁵）. Age-standardized incidence rates were 36.93/10⁵ based on the Chinese standard population（ASR China） and 35.92/10⁵ based on the world standard population （ASR world）. Cumulative incidence rate （0-74 years old） was 4.01%，and the truncated incidence rate （35-64 years old） was 73.85/10⁵. The proportion of liver cancer was 17.23%.The incidence of liver cancer and ASR China were 31.19/10⁵ and 26.01/10⁵ in urban areas，compared to 47.86/10⁵ and 44.53/10⁵ in rural areas. Crude mortality associated with liver cancer in Guangxi cancer registration areas was 34.66/10⁵（males 54.67/10⁵，females 13.02/10⁵）. Age-standardized mortality rates was 30.29/10⁵ based on the Chinese standard population （ASR China） and 29.48/10⁵ based on the world standard population （ASR world）. Cumulative mortality rate （0-74 years old） was 3.23% and truncated mortality rate（35-64 years old） was 48.12/10⁵.The proportion was 22.77%. Mortality associated with liver cancer and ASR China were 22.92/10⁵ and 18.96/10⁵ in urban areas，compared to 41.61/10⁵ and 37.94/10⁵ in rural areas.Conclusion In Guangxi，incidence of liver cancer and associated mortality are higher than the national level. Incidence and mortality of liver cancer in rural areas are higher than in urban areas. Incidence of liver cancer and associated mortality are higher in the south-central region than in the north-central region. Whether in urban or in rural areas，incidence and mortality are obviously higher in males than in females.

Key words: Cancer registry, Liver cancer, Incidence, Mortality, Guangxi