Abstract: Objective To analyze the incidence and mortality of liver cancer in Shanxi cancer registries in 2016, and to provide the strategies of prevention and treatment of liver cancer. Methods The incidence and mortality data of liver cancer in 12 cancer registries of Shanxi Province were collected with recording the incidence, mortality. The age-standardized of Chinese standard population (ASR China) and world standard population (ASR world) were calculated by the Chinese standard population in 2000 and Segi's population, respectively. The incidence and mortality rates of liver cancer were analyzed based on the stratification of the gender , age and areas (urban and rural). Results In 2016, 754 new cases of liver cancer were recorded in Shanxi cancer registries, with the incidence of 15.42/105 (male: 19.40/105, female: 11.29/105), ASR China of 10.72/105 and the ASR world of 10.75/105. The incidence in urban areas was 10.14/105, and ASR China was 6.73/105; the incidence in rural areas was 19.00/105, and ASR China was 13.48/105. A total of 761 cases died of liver cancer in Shanxi cancer registries, with the mortality rate of 15.56/105 (male: 19.80/105, female: 11.17/105), ASR China of 10.71/105 and the ASR world of 10.86/105. The mortality rate of urban areas was 14.90/105, and ASR China was 9.86/105; the mortality rate of rural areas was 16.01/105, and ASR China was 11.37/105. The incidence and mortality of liver cancer both increased with age, and the incidence increased more significantly after the age of 35. The incidence and mortality in Shanxi Province reached the peak in the age group of 80 years and 85 years, respectively, and the male was higher than the female. Conclusions The incidence and mortality rates of liver cancer in Shanxi cancer registries are lower than the national average, the male is higher than the female, and higher in rural areas than in urban areas. Therefore, the prevention and treatment of liver cancer should focus on males and people in rural areas.

Key words: Liver cancer, Incidence, Mortality, Cancer registries, Shanxi