Abstract: Objective To analyze the epidemiological characteristics and disease burden of malignant tumors in Guangxi cancer registration areas in 2017, and to provide evidence for prevention and treatment of malignant tumors. Methods According to the tumor incidence and death data reported by 33 cancer registration areas in Guangxi in 2017, the incidence, mortality and corresponding standardized rates of Chinese population (ASR China) and world population (ASR World) were calculated to analyze the epidemiological characteristics of malignant tumors. The years of lived with disability (YLDs), years of life lost (YLLs) and disability-adjusted life years (DALYs) related to cancer were collated to assess the disease burden of malignant tumors. Results In 2017, a total of 34,10⁵ new cases of malignant tumors were reported in Guangxi cancer registration areas, with a crude incidence of 243.67/105 , ASR China of 201.71/10⁵ and ASR World of 196.51/10⁵ . A total of 20,709 deaths were reported, with a crude mortality rates of 147.96/105 , ASR China of 117.81/10⁵  and ASR World of 116.26/10⁵ . The cancer of the lung, liver, female breast, colorectum, cervix, stomach, nasopharynx, uterus, prostate and ovary were the top ten for malignant tumors incidence, accounting for 74.0% of total cancer cases. The cancer of liver, lung, colorectum, stomach, female breast, cervix, nasopharynx, esophagus, leukemia and brain were the ten leading causes of cancer deaths, accounting for 82.0% of total cancer deaths. Cancers resulted in 301,738.2 DALYs in Guangxi in 2017, the DALYs rates were 2,155.86 DALYs per 105  persons. The top 10 cancers in DALYs rate were the cancers of liver, lung, colorectum, stomach, nasopharynx, female breast, leukemia, brain, esophagus and cervix. Conclusions In 2017, the incidence, mortality, and DALYs rates of malignant tumors in Guangxi were all at a high level. The lung cancer, liver cancer, colorectum cancer, nasopharynx cancer, female breast cancer and cervix cancer are the major malignant tumor for prevention and treatment in Guangxi.

Key words: Malignant tumor, Epidemiological characteristics, Disease burden, Incidence rate, Mortality rate, DALYs