Abstract:

Objective To determine the value of  contrast-enhanced and routine transrectal ultrasound combination in the diagnosis of prostate cancer. Method A total of 70 men with suspected prostate cancer were examined by both routine and contrast-enhanced transrectal ultrasound at our hospital. Diagnosis was confirmed by prostate biopsy. Result The pathological positive rate was 62.9%. A total of 37 patients were diagnosed with prostate cancer by contrast-enhanced combined routine transrectal ultrasound，while 21 were diagnosed with prostate cancer by routine transrectal ultrasound. Significantly different values of diagnostic performance parameters were obtained for the contrast-enhanced combined routine technique vs. the routine technique（all P＜0.05）：sensitivity，84.1% vs 47.7%；specificity，69.2% vs 53.8%；positive predictive value，82.2% vs 63.6%；negative predictive value，72.0% vs 37.8%；and pathological coincidence rate，78.6% vs 50.0%. Conclusion Contrast-enhanced combined routine transrectal ultrasound shows higher diagnostic performance than routine transrectal ultrasound for diagnosing prostate cancer.

Key words: Prostatic neoplasm, Contrast-enhanced transrectal ultrasound, Routine transrectal ultrasound, Diagnosis