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中国癌症防治杂志

中国癌症防治杂志 ›› 2012, Vol. 4 ›› Issue (2): 194-196.doi: 10.3969/j.issn.1674-5671.2012.02.24

• 临床研究 • 上一篇    下一篇

腋窝良恶性淋巴结的MR弥散加权成像研究

  

  1.  广西医科大学附属肿瘤医院医学影像学中心
  • 出版日期:2012-06-25 发布日期:2012-07-03
  • 通讯作者: 苏丹柯 E-mail:sudanke33@sina.com

Evaluation of axillary lymph node metastases using diffusion-weighted imaging

  • Online:2012-06-25 Published:2012-07-03

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摘要： 目的 评价MR弥散加权成像（diffusion-weighted imaging, DWI）对乳腺癌淋巴结转移的诊断价值。方法 收集24例乳腺癌伴腋窝淋巴结肿大患者，行常规MR及MR弥散加权成像序列扫描，测量淋巴结的表观弥散系数（apparent diffusion coefficient, ADC），结合术后病理结果进行对照分析。结果 转移性淋巴结与良性增生淋巴结的ADC值分别为（0.796±0.171）×10-3mm2/s和（1.058±0.234）×10-3mm2/s，差异有统计学意义（P＜0.05）；以0.854×10-3mm2/s作为ADC值诊断淋巴结转移的阈值，其灵敏度、特异度和准确度分别为73.91%、86.96%和80.43%。结论 弥散加权成像对乳腺癌淋巴结转移灶的诊断具有重要价值。

关键词: 乳腺癌, 淋巴结, 弥散加权成像, 表观弥散系数

Abstract: Objective To evaluate the ability of diffusion-weighted imaging（DWI） to diagnose axillary lymph node metastases in patients with breast cancer. Methods Preoperative conventional MR and DWI imaging was performed on 24 patients with breast can-cer and enlarged axillary lymph nodes.The apparent diffusion coefficient （ADC） of axillary lymph nodes was determined，and its rela-tionship to histopathologic findings was analyzed. Results The ADC value of metastatic lymph nodes （0.796±0.171） ×10-3mm2/s was significantly lower than that of benign nodes（1.058±0.234，P<0.05）×10-3mm2/s.With the threshold ADC value at 0.854×10-3mm2/s for diagnosing lymph node metastasis，the sensitivity，specificity and accuracy were，respectively，73.91%，86.96% and 80.43%. Conclusion DWI is useful for detecting axillary lymph node metastases in patients with breast cancer.

Key words:  Breast cancer, Lymph node, Diffusion-weighted imaging, Apparent diffusion coefficient