Abstract:

Objective  To analyze the incidence and mortality of colorectal cancer in Guangxi in 2014 based on areas with cancer registry reporting. Methods A total of 11 cancer registries of Guangxi reported cancer data for 2014，and 9 registries were found to conform to data quality criteria of the National Central Cancer Registry（NCCR）. Data from these 9 registries were analyzed to determine incidence and mortality of colorectal cancer stratified by areas（urban/rural），sex，and age group，and cumulative incidence/mortality rates，proportions，and truncated incidence/mortality rates were calculated. The Chinese population census in 2000 and Segi′s population were used for age-standardized incidence/mortality rates. Results  The  number of new colorectal cancer cases was 1，716（males 1，039，females 677） from 9 registry areas. The crude incidence of colorectal cancer in Guangxi cancer registration areas was 24.74/105，age-standardized incidence rates was 19.68/105 based on the Chinese standard population（ASR China）and 19.37/105 based on the world standard population（ASR world），and the colorectal cancer incidence rate of males was significantly higher than females（28.73%  vs 20.40%，χ²=48.33，P<0.001）. The incidence of colorectal cancer and ASR China were 36.19/105 and 27.45/105 in urban areas，compared to 19.24/105 and 16.07/105 in rural areas. The total number of colorectal cancer-related deaths was 827（males 518，females 309）. Crude mortality associated with colorectal cancer in Guangxi cancer registration areas was 11.93/105， age-standardized mortality rate was 9.06/105 based on the Chinese standard population（ASR China）and 9.00/105 based on the world standard population （ASR world），and the colorectal cancer mortality rate of males was significantly higher than females（14.32%  vs 9.31%，χ²=36.400，P<0.001）. Mortality associated with colorectal cancer and ASR China were 17.63/105 and 13.21/105 in urban areas，compared to 9.18/105 and 7.13/105 in rural areas. Conclusions In Guangxi，incidence of colorectal cancer and associated mortality are obviously higher in males than in females. The incidence and mortality of colorectal cancer are higher in urban areas than in rural areas.Urban male over 45 years old is the the main target population for cancer prevention and treatment.

Key words: Cancer register, Colorectal cancer, Incidence, Mortality, Guangxi