Abstract: Objective To analyze the results of high risk assessment and clinical screening of cancer screening program in urban Guangxi from 2014 to 2017. Methods The aged 40 to 74 residents from Xixiangtang district and Qingxiu district in Nanning of Guangxi from November 2014 to August 2017 were recruited using the cluster sample method. The “Cancer Prevention Risk Assessment Questionnaire” was used in the survey to assess the five major cancers(lung cancer, upper gastrointestinal cancer, liver cancer, colorectal cancer and breast cancer) high-risk groups, then clinical screening was conducted, and the high risk of each cancer risk rate, screening participation rate and detection rate were analyzed. Results A total of 152 630 participants completed the questionnaires and risk assessments and 72 376(47.62%) people at high-risk. Among, The high risk rates of lung cancer, esophageal cancer, stomach cancer, liver cancer, colorectal cancer and female breast cancer were 25.66%, 17.39%, 26.11%, 28.95%, 22.19% and 32.76%, respectively;men had a higher risk of lung cancer than women, and women had a higher risk of esophageal cancer, stomach cancer, liver cancer and colorectal cancer than men. The clinical screening participation rates of lung cancer, breast cancer, liver cancer, colorectal cancer and upper gastrointestinal cancer were 26.42%, 25.18%, 25.03%, 11.31% and 7.68%, respectively. Clinical screening results showed that the detection rates of suspected lung cancer, suspected liver cancer, breast BI-RADS grade 4-5, colorectal cancer and upper digestive tract cancer were 0.58%, 0.05%, 2.79%, 0.13% and 0.12%, respectively. Conclusions From 2014 to 2017, the participation rate of cancer screening and the detection rate of positive lesions of cancer screening program in urban of Guangxi from 2014 to 2017 are not high. Therefore, it is necessary to improve the awareness of cancer prevention and the participation rate of physical examination and screening in high-risk area, further identify the high-risk cancer population and improve the screening effect.

Key words: Guangxi, Urban, Cancer screening, Risk assessment