Abstract: Objective To analyze the incidence and mortality of malignant tumors in the cancer registration areas of Hainan province in 2017. Methods The incidence and mortality of malignant tumors and population data in 6 cancer registries in Hainan province in 2017 were collected, and stratified by sex, region and age after data quality verification. The crude incidence and mortality rate, composition ratio, cumulative rate of 0-74 years old and standardized rate were calculated, and the top 10 malignant tumors in incidence and death were summarized. Results In 2017, the registered tumor population accounted for 23.19% of the total population in Hainan province, and there were 5, 504 new cases of malignant tumors. The incidence, age⁃standardized incidence rate by Chinese standard population (ASIRC), age⁃standardized incidence rate by Segi's world population (ASIRW) and cumulative rate of 0-74 years old were 260.71/10⁵, 213.29/10⁵, 207.88/10⁵ and 24.32%, respectively. There were 2, 585 deaths due to malignant tumors, and the mortality, ASIRC rate, ASIRW rate and cumulative rate of 0-74 years old were 122.44/10⁵, 95.27/10⁵, 94.05/10⁵ and 11.05%, respectively. The incidence and mortality rate of males were higher than those of females, the incidences of both males and females began to increase from the age group of 25- years, reached the peak in the age group of 65- and 80- years, respectirely; The mortality rate increased from 35- years and reached the peak in the age group of 80- years. The incidence rate was higher in urban areas than in rural areas, whereas the mortality rate was lower in urban areas than in rural areas. The top 10 malignant tumors with regard to incidence were liver cancer, lung cancer, colorectal cancer, breast cancer, gastric cancer, nasopharyngeal cancer, esophageal cancer, oral cancer, cervical cancer, and thyroid cancer, while the top 10 malignancies in mortality were liver cancer, lung cancer, gastric cancer, colorectal cancer, nasopharyngeal cancer, esophageal cancer, brain tumor, laryngeal cancer, lymphoma, and breast cancer. Conclusions The age⁃specific incidence and mortality of malignant tumors in Hainan province showed an increasing trend in 2017, and the affected population developed gradually towards younger. The incidence and mortality of males were higher than those of females. The incidence in urban areas was higher than in rural areas, while the mortality showed an opposite trend. Cancers such as liver cancer, lung cancer, colorectal cancer, breast cancer, and gastric cancer are the focus of prevention and treatment , the prevention and control needs to be further strengthened.

Key words: Malignant tumor, Cancer registration, Incidence, Mortality, Hainan