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中国癌症防治杂志

中国癌症防治杂志 ›› 2021, Vol. 13 ›› Issue (2): 138-143.doi: 10.3969/j.issn.1674-5671.2021.02.05

• 癌情监测 • 上一篇    下一篇

2010—2016年广西肿瘤登记地区肝癌发病和死亡分析及变化趋势

  

  1. 广西医科大学附属肿瘤医院；广西癌症中心；广西壮族自治区肿瘤防治研究工作领导小组办公室
  • 出版日期:2021-04-25 发布日期:2021-04-30
  • 通讯作者: 余家华 E-mail：gxzlfb@163.com
  • 基金资助:
    国家自然科学基金项目（81860596）；广西卫生和计划生育委员会自筹经费科研课题（Z20180649）

Analysis of incidence and mortality of liver cancer in cancer registration areas in Guangxi,2010—2016

  • Online:2021-04-25 Published:2021-04-30

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摘要： 目的 分析2010—2016年广西肿瘤登记地区肝癌发病和死亡特征及其变化趋势，为广西制定肝癌防控措施提供依据。方法 收集2010—2016年广西肿瘤登记地区上报的恶性肿瘤发病与死亡资料，计算肝癌发病率、死亡率、构成比、0~74岁累积率、35~64岁截缩率，按地区（城市/农村）、性别和年龄分层。采用2000年中国人口普查和Segi's世界人口计算年龄标准化率。采用Joinpoint模型对肝癌发病率和死亡率进行趋势分析。结果 2010—2016年广西肿瘤登记地区肝癌发病率为41.79/10万，中标率为34.86/10万，世标率为33.45/10万，0~74岁累积率为3.79%，35~64岁截缩率为68.60/10万；死亡率为34.56/10万，中标率为28.63/10万，世标率为27.63/10万，0~74岁累积率为3.12%，35~64岁截缩率为54.48/10万；男性发病率和死亡率均高于女性，农村地区高于城市地区。2010—2016年广西肿瘤登记地区肝癌发病和死亡水平呈明显上升趋势，发病率的APC为5.38%（95%CI：2.56%~8.29%，P<0.05），死亡率的APC为9.23%（95%CI：3.83%~14.92%，P<0.05）。结论 2010—2016年广西肿瘤登记地区肝癌发病率和死亡率呈上升趋势，应针对肝癌致病因素和流行特征采取有效措施予以防控，35岁及以上男性（尤其农村）是开展早期筛查和干预的重点人群。

关键词: 肝癌, 发病率, 死亡率, 肿瘤登记, 广西

Abstract: Objective To analyze the characteristics and trends of the incidence and mortality of liver cancer in the cancer registration areas in Guangxi from 2010 to 2016, and to provide the basis for developing the prevention and control measures of liver cancer in Guangxi. Methods The incidence and mortality data of cancer in the cancer registration areas in Guangxi from 2010 to 2016 were collected, and the incidence rate, mortality rate, proportionate, cumulative rate (0-74 years old) and truncated rate (35-64 years old) were calculated by areas (urban/rural), gender and age stratification. The age?standardized rates were calculated by the 2000 national census (ASR China) and Segi's standard population(ASR world). The trend of incidence and mortality of liver cancer was analyzed by Joinpoint model. Results From 2012 to 2016, the incidence of liver cancer in Guangxi was 41.79/105, the ASR China 34.86/105, the ASR world 33.45/105, the cumulative rate (0-74 years old) 3.79%, and the truncated rate (35-64 years old) 68.60/105. The mortality rate was 34.56/105, the ASR China 28.63/105, the ASR world 27.63/105, the cumulative rate (0-74 years old) 3.12%, and the truncated rate (35-64 years old) 54.48/105. The incidence and mortality rates of males were higher than those of females, and those in rural areas were higher than those in urban areas. From 2010 to 2016, the incidence and mortality levels of liver cancer in Guangxi cancer registration areas showed a significantly increasing trend, with the incidence and mortality APC of 5.38% (95%CI: 2.56%-8.29%, P<0.05) and 9.23% (95%CI:3.83%-14.92%, P<0.05), respectively. Conclusions From 2010 to 2016, the incidence and mortality of liver cancer in Guangxi cancer registration areas showed an increasing trend. Therefore, effective measures should be taken to prevent and control liver cancer according to the pathogenic factors and epidemic characteristics of liver cancer. Men aged 35 and above (especially in rural areas) are the key population for early screening and intervention.

Key words: Liver cancer, Incidence, Mortality, Cancer registration, Guangxi