Abstract:

 Objective To compare the influence of enteral and parenteral nutrition（EN/PN） on intestinal function，postoperative hospitalization duration and immune state of patients undergoing radical gastrectomy. Methods A total of 80 patients who underwent radical gastrectomy from January 2011 to May 2014 were recruited as research subjects，and they were randomly divided into EN and PN groups. Intestinal function， postoperative hospitalization duration and immune state were measured in each group and compared. Results Intestinal ventilation time and postoperative hospitalization duration were significantly shorter for the EN group than for the PN group（P<0.05）. Levels of IgA，IgG，IgM，and CD3+ at 1 and 7 d after surgery were significantly higher in the EN group（P<0.05）， as was the level of CD4⁺ at 7 d after surgery. The two groups showed similar levels of NK cells and CRP at 1 and 7 d after surgery，as well as similar levels of CD4⁺ at 1 d after surgery （P>0.05）. Conclusion EN may be associated with greater recovery of intestinal and immune function after radical gastrectomy than PN.

Key words: Gastric neoplasm, Radical surgery, Immune function, Enteral nutrition, Parenteral nutrition