Objective To explore the relationship between the 19007C/T polymorphism in the excision repair cross-complementation group 1（ERCC1）gene and response of patients with epithelial ovarian cancer to platinum-based combination chemotherapy. Methods Pubmed, HuGENet and Wanfang databases were systematically searched, and  Stata 11.0 meta-analysis was used to explore relationships of different genotypes of the 19007C/T polymorphism and chemotherapy response. Results 7 eligible studies involving 711 patients were retrieved. No significant associations were found in meta-analyses of ERCC1 gene 19007C / T polymorphism and chemosensitivity to Cisplatin.Race，Specimen source，whether the hardy Weinberg equilibrium and gene detection method were stratified analysis in each model，but there was no statistical significance. Conclusion This meta-analysis did not identify any significant relationships between the ERCC1 19007C/T polymorphism and response of patients with epithelial ovarian cancer to platinum-based combination chemotherapy. Large，well-designed studies are needed to verify these findings.