Abstract:

Objective This study reviewed the frequencies of each tumor stage and each type of primary treatment modality among patients with primary hepatocellular carcinoma（HCC）treated at a tertiary tumor hospital over the last decade. Methods Baseline data of patients with primary HCC treated between January 2003 and October 2013 were retrospectively collected. Tumor stage was determined according to the Barcelona Clinic Liver Cancer（BCLC） staging system. Results A total of 6，241 patients with primary HCC were included in the analysis，of whom 28.9% were in stage BCLC-0/A；16.2%，BCLC-B；53.6%，BCLC-C；and 1.3%，BCLC-D. Treatment modalities applied to this patient group were as follows：hepatic resection，33.3%；interventional therapy，36.7%；radiotherapy，2.2%；ablation therapy，0.9%；systemic chemotherapy，8.8%；traditional herbal medicine therapy，4.2%；targeted drug therapy，0.1%；and no treatment， 13.8%.Hepatic resection was the most frequent therapy for patients with BCLC-0/A/B disease， and interventional treatment was the first-line therapy for patients with BCLC-C disease. Conclusion Prevalence of stage BCLC-B and-C disease was high among our HCC patients.Hepatic resection and interventional treatment are first-line therapies for both stages.

Key words: Liver neoplasm, Barcelona Clinic liver cancer, Treatment, Survey and analysis