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Chinese Journal of Oncology Prevention and Treatment ›› 2014, Vol. 6 ›› Issue (1): 74-77.doi: 10.3969/j.issn.1674-5671.2014.01.19

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Effects of intraoperative and postoperative hypothermia on recovery in patients with large hepatocellular carcinoma undergoing hepatectomy

  

  • Online:2014-03-25 Published:2014-04-10

Abstract: Objective To investigate the effects of intraoperative and postanesthesia hypothermia on recovery in patients with large hepatocellular carcinoma(HCC) undergoing hepatectomy. Methods A total of 160 hypothermic patients were divided into three groups according to the severity of hypothermia:T<35℃(n=41,group A1),35-35.5℃(n=85,A2) and 35.6-35.9℃(n=34,A3).In a separate analysis,patients were divided into three groups according to the duration of hypothermia::<1 h (n=35,B1),1-2 h(n=47,B2),and>2 h(n=78,B3).Postanesthesia recovery time,first postoperative peritoneal drainage volume,5th postoperative ALT and AST levels,wound healing time and duration of postoperative hospitalization were compared among the groups. Results Anesthestia recovery time was longer in A1 than in the other A groups, and longer in B3 than in the other B groups.First postoperative peritoneal drainage was higher and 5th postoperative ALT levels were lower in A1 and B3 than in the respective A and B groups(P<0.05).Group A3 showed the lowest 5th postoperative ALT level and longest wound healing and postoperative hospitalization(P<0.05). Conclusion Body temperature <35℃ significantly affects patient recovery.Greater attention should be paid to body temperature monitoring and effective rewarming in order to minimize postoperative complications due to hypothermia.   

Key words: Liver neoplasm, Hypothermia, Tympanic Temperature, Recovery, Nursing