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中国癌症防治杂志

中国癌症防治杂志 ›› 2024, Vol. 16 ›› Issue (2): 186-192.doi: 10.3969/j.issn.1674-5671.2024.02.08

• 临床研究 • 上一篇    下一篇

高钠饮食对我国居民1990—2019年胃癌疾病负担的影响及趋势分析

  

  1. 河南省平顶山市第一人民医院消化内科；河南省人民医院，郑州大学人民医院消化内科
  • 出版日期:2024-04-25 发布日期:2024-05-08
  • 通讯作者: 刘博伟 E-mail：lbwshsmu@126.com
  • 基金资助:
    河南省医学科技攻关计划省部共建重点项目（SBGJ202102042）

Effects of high sodium diet on the burden of gastric cancer in Chinese residents and a trend analysis,1990—2019

  • Online:2024-04-25 Published:2024-05-08

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摘要： 目的 分析高钠饮食对我国胃癌疾病负担的影响情况，为胃癌高危人群防治策略优化提供参考。 方法 采用2019全球疾病负担研究（global burden of disease study 2019，GBD 2019）中的中国胃癌疾病负担数据，以Joinpoint回归模型分析1990—2019年我国高钠饮食所致胃癌死亡率和伤残调整生命年（disability⁃adjusted life⁃years，DALYs）的变化及其趋势，以平均年度变化百分比（average annual percent change，AAPC）和95%可信区间（confidence interval，CI）表示各相邻年份间构成比的变化量。 结果 我国高钠饮食所致胃癌死亡例数和粗死亡率自1990年的27 226 例（占我国胃癌总死亡例数8.913%）、2.300/10万上升至2019年的37 131例（占我国胃癌总死亡数8.808%）、2.611/10万，但DALYs率从62.048/10万下降至61.434/10万。1990—2019年我国居民高钠饮食所致胃癌合计标化死亡率逐年下降1.716%，其中男性逐年下降1.221%，女性逐年下降2.661%（均P<0.001）；标化DALYs率逐年下降2.005%，其中男性逐年下降1.495%，女性逐年下降3.067%。各年龄组DALYs率均呈下降趋势（均P<0.01），其中55~59岁居民的DALYs率下降速度最快（AAPC=-2.547%），80岁及以上居民的DALYs率下降速度较慢（AAPC=-0.702%）。我国居民高钠饮食所致胃癌标化DALYs率逐年下降（AAPC=-2.005%），下降速度高于中低和低社会人口指数（socio⁃demographic index，SDI）国家或地区（AAPC=-1.209%、 -1.119%），但低于全球以及高、中高、中SDI国家或地区的平均水平（AAPC=-2.094%、-3.166%、-2.361%、-2.090%）。 结论 我国居民高钠饮食所致的胃癌疾病负担逐年下降但水平仍较高，男性高于女性，老年男性人群是重点干预人群，应加强减盐饮食干预，以降低胃癌疾病负担。

关键词: 胃癌, 疾病负担, 伤残调整生命年, 高钠饮食, 生活方式

Abstract: Objective To analyze the effects of high sodium diet on the burden of gastric cancer in China and their developing trends, and to provide reference for the optimization of prevention and treatment strategies for high⁃risk populations of gastriv cancer．Methods Based on the data of global burden of disease study 2019 (GBD 2019), the Joinpoint regression model was used to analyze the mortality rate and disability⁃adjusted life⁃years (DALYs) rate of gastric cancer caused by high sodium diet in China from 1990 to 2019. The average annual percent change (AAPC) and 95% confidence interval (CI) were used to represent the change in composition ratio between adjacent years. Results The death rate and crude mortality rate of gastric cancer caused by high sodium diet among Chinese residents increased from 27 226 cases (accounted for 8.913% of the total death of gastric cancer in China) and 2.300/105 in 1990 to 37 131 cases (accounted for 8.808% of the total deaths of gastric cancer in China) and 2.611/105 in 2019, whereas the DALYs rate decreased from 62.048/105 to 61.434/105. The standardized mortality rate of gastric cancer caused by high sodium diet among Chinese residents decreased by 1.716% year by year, with 1.221% for males and 2.661% for females (all P<0.001) from 1990 to 2019. The standardized DALYs rate decreased by 2.005% year by year, with 1.495% for males and 3.067% for females. The DALYs rate in all age groups showed a downward trend (all P<0.001), and the rate of DALYs decreased most rapidly in the age group of 55-59 (AAPC=-2.547%), and slowly in the age group of 80 and above (AAPC=-0.702%). The standardized DALYs rate of stomach cancer caused by high sodium diet among Chinese residents decreased year by year. The rate of decline was higher than that of low and medium social demographic index (SDI) countries or regions (AAPC=-1.209%, -1.119%), but lower than the global average and the average level of high, medium and medium SDI countries or regions (AAPC=-2.094%, -3.166%, -2.361%, -2.090%). Conclusions The burden of gastric cancer caused by high sodium diet among Chinese residents has decreased year by year, but still on a high level; the level of male are higher than that of female, The elderly male population is the key intervention group, and dietary salt reduction intervention should be strengthened to reduce the burden of gastric cancer.

Key words: Gastric cancer, Disease burden, Disability-adjusted life-years, High sodium diet, Life style

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  • 引用本文

    牛省利, 刘博伟. 高钠饮食对我国居民1990—2019年胃癌疾病负担的影响及趋势分析[J]. 中国癌症防治杂志, 2024, 16(2): 186-192.

    NIU Shengli, LIU Bowei. Effects of high sodium diet on the burden of gastric cancer in Chinese residents and a trend analysis,1990—2019[J]. Chinese Journal of Oncology Prevention and Treatment, 2024, 16(2): 186-192.