关键词: 胃癌, No.14v组淋巴结, 危险因素, 预后

Abstract: Objective To investigate the risk factors and to perform prognostic analysis of lymph node metastasis in the No.14v group in gastric cancer. Methods The clinical data of 72 gastric cancer patients who underwent radical gastrectomy with lymph node in the No.14v group dissection were analyzed retrospectively. Logistic regression was used to analyze the factors affecting lymph node metastasis in the No.14v group，Cox regression was used to analyze the relationship between lymph node metastasis in the No.14v group and prognosis. Results The lymph node metastasis rate in the No.14v group was 25.0%（18/72）. Logistic regression analysis showed that Borromann classification Ⅲ-Ⅳ（OR=81.508，95%CI：4.805-1 382.635，P=0.002），distant metastasis（OR=11.494，95%CI：1.085-121.723，P=0.043），and TNM stages Ⅲ-Ⅳ（OR=8.101，95%CI：1.355-48.437，P=0.005） were independent risk factors affecting lymph node metastasis in the No.14v group. The median overall survival of patients with lymph node metastasis in the No.14v group was lower than that in the non-metastatic group（22 months vs 33 months，χ²= 22.737，P<0.001）. Multivariate Cox regression analysis showed that lymph node metastasis in the No.14v group was an independent influencing factor for the overall survival of patients（HR=2.881， 95%CI：1.222-6.793，P=0.016）. Conclusions Patients with lymph node metastasis in the No.14v group have a poor prognosis in gastric cancer，and the independent risk factors for lymph node metastasis in the No.14v group include Borromann classification Ⅲ-Ⅳ，distant metastasis，and TNM stage Ⅲ-Ⅳ.

Key words: Gastric cancer, No.14v lymph node, Risk factors, Prognosis